Revisiting gap locations in amino acid sequence alignments and a proposal for a method to improve them by introducing solvent accessibility

In comparative modeling, the quality of amino acid sequence alignment still constitutes a major bottleneck in the generation of high quality models of protein three-dimensional (3D) structures. Substantial efforts have been made to improve alignment quality by revising the substitution matrix, intro...

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Detalles Bibliográficos
Autores principales: Hijikata, Atsushi, Yura, Kei, Noguti, Tosiyuki, Go, Mitiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110861/
https://www.ncbi.nlm.nih.gov/pubmed/21465562
http://dx.doi.org/10.1002/prot.23011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110861/
https://www.ncbi.nlm.nih.gov/pubmed/21465562
http://dx.doi.org/10.1002/prot.23011

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