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Statistical issues in the use of dynamic allocation methods for balancing baseline covariates
BACKGROUND: The procedure for allocating patients to a treatment arm in comparative clinical trials is frequently chosen with only minor deliberation. This decision may, however, ultimately impact the trial inference, credibility, and even validity of the trial analysis. Cancer researchers are incre...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111167/ https://www.ncbi.nlm.nih.gov/pubmed/21540857 http://dx.doi.org/10.1038/bjc.2011.157 |