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Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas
Local recurrence of glioblastomas is a major cause of patient mortality after definitive treatment. This review discusses the roles of the chemokine stromal cell-derived factor-1 and its receptor CXC chemokine receptor 4 (CXCR4) in affecting the sensitivity of glioblastomas to irradiation. Blocking...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111201/ https://www.ncbi.nlm.nih.gov/pubmed/21587260 http://dx.doi.org/10.1038/bjc.2011.169 |