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Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas

Local recurrence of glioblastomas is a major cause of patient mortality after definitive treatment. This review discusses the roles of the chemokine stromal cell-derived factor-1 and its receptor CXC chemokine receptor 4 (CXCR4) in affecting the sensitivity of glioblastomas to irradiation. Blocking...

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Detalles Bibliográficos
Autores principales: Tseng, D, Vasquez-Medrano, D A, Brown, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111201/
https://www.ncbi.nlm.nih.gov/pubmed/21587260
http://dx.doi.org/10.1038/bjc.2011.169