Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst formation throughout the kidney parenchyma. It is caused by mutations in either of two genes, PKD1 and PKD2. Mice that lack functional Pkd1 (Pkd1(-/-)), develop rapidly progressive cystic disease during embryog...

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Detalles Bibliográficos
Autores principales: Pandey, Priyanka, Qin, Shan, Ho, Jacqueline, Zhou, Jing, Kreidberg, Jordan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111376/
https://www.ncbi.nlm.nih.gov/pubmed/21518438
http://dx.doi.org/10.1186/1752-0509-5-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111376/
https://www.ncbi.nlm.nih.gov/pubmed/21518438
http://dx.doi.org/10.1186/1752-0509-5-56

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