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Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

BACKGROUND: The drug/metabolite transporter superfamily comprises a diversity of protein domain families with multiple functions including transport of nucleotide sugars. Drug/metabolite transporter domains are contained in both solute carrier families 30, 35 and 39 proteins as well as in acyl-malon...

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Detalles Bibliográficos
Autores principales: Västermark, Åke, Almén, Markus Sällman, Simmen, Martin W, Fredriksson, Robert, Schiöth, Helgi B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111387/
https://www.ncbi.nlm.nih.gov/pubmed/21569384
http://dx.doi.org/10.1186/1471-2148-11-123