Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs

BACKGROUND: Numerous immune-mediated diseases have been associated with the class I and II HLA genes located within the major histocompatibility complex (MHC) consisting of highly polymorphic alleles encoded by the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci. Genotyping for HLA alleles is complex and...

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Detalles Bibliográficos
Autores principales: Zhang, Xinyi Cindy, Li, Shuying Sue, Wang, Hongwei, Hansen, John A, Zhao, Lue Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111398/
https://www.ncbi.nlm.nih.gov/pubmed/21518453
http://dx.doi.org/10.1186/1471-2156-12-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111398/
https://www.ncbi.nlm.nih.gov/pubmed/21518453
http://dx.doi.org/10.1186/1471-2156-12-39

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