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Computational Prediction of Intronic microRNA Targets using Host Gene Expression Reveals Novel Regulatory Mechanisms

Approximately half of known human miRNAs are located in the introns of protein coding genes. Some of these intronic miRNAs are only expressed when their host gene is and, as such, their steady state expression levels are highly correlated with those of the host gene's mRNA. Recently host gene e...

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Detalles Bibliográficos
Autores principales: Radfar, M. Hossein, Wong, Willy, Morris, Quaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111417/
https://www.ncbi.nlm.nih.gov/pubmed/21694770
http://dx.doi.org/10.1371/journal.pone.0019312