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Computational Prediction of Intronic microRNA Targets using Host Gene Expression Reveals Novel Regulatory Mechanisms
Approximately half of known human miRNAs are located in the introns of protein coding genes. Some of these intronic miRNAs are only expressed when their host gene is and, as such, their steady state expression levels are highly correlated with those of the host gene's mRNA. Recently host gene e...
Autores principales: | Radfar, M. Hossein, Wong, Willy, Morris, Quaid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111417/ https://www.ncbi.nlm.nih.gov/pubmed/21694770 http://dx.doi.org/10.1371/journal.pone.0019312 |
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