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Epigenetic Dysregulation in Mesenchymal Stem Cell Aging and Spontaneous Differentiation
BACKGROUND: Mesenchymal stem cells (MSCs) hold great promise for the treatment of difficult diseases. As MSCs represent a rare cell population, ex vivo expansion of MSCs is indispensable to obtain sufficient amounts of cells for therapies and tissue engineering. However, spontaneous differentiation...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111432/ https://www.ncbi.nlm.nih.gov/pubmed/21694780 http://dx.doi.org/10.1371/journal.pone.0020526 |