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A Genetically Encoded Tool Kit for Manipulating and Monitoring Membrane Phosphatidylinositol 4,5-Bisphosphate in Intact Cells

BACKGROUND: Most ion channels are regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)) in the cell membrane by diverse mechanisms. Important molecular tools to study ion channel regulation by PtdIns(4,5)P(2) in living cells have been developed in the past. These include fluorescent P...

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Detalles Bibliográficos
Autores principales: Hertel, Fabian, Switalski, Agathe, Mintert-Jancke, Elisa, Karavassilidou, Katharina, Bender, Kirsten, Pott, Lutz, Kienitz, Marie-Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111442/
https://www.ncbi.nlm.nih.gov/pubmed/21695261
http://dx.doi.org/10.1371/journal.pone.0020855