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Impaired Proteostasis Contributes to Renal Tubular Dysgenesis

Protein conformational disorders are associated with the appearance, persistence, accumulation, and misprocessing of aberrant proteins in the cell. The etiology of renal tubular dysgenesis (RTD) is linked to mutations in the angiotensin-converting enzyme (ACE). Here, we report the identification of...

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Detalles Bibliográficos
Autores principales: de Oliveira, Rita Machado, Marijanovic, Zrinka, Carvalho, Filipe, Miltényi, Gabriel Miltenberger, Matos, Joana Estevão, Tenreiro, Sandra, Oliveira, Sónia, Enguita, Francisco Javier, Stone, Rosário, Outeiro, Tiago Fleming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111453/
https://www.ncbi.nlm.nih.gov/pubmed/21695262
http://dx.doi.org/10.1371/journal.pone.0020854