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Endothelial and Macrophage-Specific Deficiency of P38α MAPK Does Not Affect the Pathogenesis of Atherosclerosis in ApoE(−/−) Mice

BACKGROUND: The p38α Mitogen-Activated Protein Kinase (MAPK) regulates stress- and inflammation-induced cellular responses. Factors implicated in the development of atherosclerosis including modified low-density lipoprotein (LDL), cytokines and even shear stress induce p38 activation in endothelial...

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Detalles Bibliográficos
Autores principales: Kardakaris, Rozina, Gareus, Ralph, Xanthoulea, Sofia, Pasparakis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111465/
https://www.ncbi.nlm.nih.gov/pubmed/21695272
http://dx.doi.org/10.1371/journal.pone.0021055