The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

PB1-F2 is a 90 amino acid protein that is expressed from the +1 open reading frame in the PB1 gene of some influenza A viruses and has been shown to contribute to viral pathogenicity. Notably, a serine at position 66 (66S) in PB1-F2 is known to increase virulence compared to an isogenic virus with a...

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Detalles Bibliográficos
Autores principales: Varga, Zsuzsanna T., Ramos, Irene, Hai, Rong, Schmolke, Mirco, García-Sastre, Adolfo, Fernandez-Sesma, Ana, Palese, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111539/
https://www.ncbi.nlm.nih.gov/pubmed/21695240
http://dx.doi.org/10.1371/journal.ppat.1002067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111539/
https://www.ncbi.nlm.nih.gov/pubmed/21695240
http://dx.doi.org/10.1371/journal.ppat.1002067

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