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BiP and Multiple DNAJ Molecular Chaperones in the Endoplasmic Reticulum Are Required for Efficient Simian Virus 40 Infection

Simian virus 40 (SV40) is a nonenveloped DNA virus that traffics through the endoplasmic reticulum (ER) en route to the nucleus, but the mechanisms of capsid disassembly and ER exit are poorly understood. We conducted an unbiased RNA interference screen to identify cellular genes required for SV40 i...

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Detalles Bibliográficos
Autores principales: Goodwin, Edward C., Lipovsky, Alex, Inoue, Takamasa, Magaldi, Thomas G., Edwards, Anne P. B., Van Goor, Kristin E. Y., Paton, Adrienne W., Paton, James C., Atwood, Walter J., Tsai, Billy, DiMaio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111607/
https://www.ncbi.nlm.nih.gov/pubmed/21673190
http://dx.doi.org/10.1128/mBio.00101-11