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Type III Secretion Is Essential for the Rapidly Fatal Diarrheal Disease Caused by Non-O1, Non-O139 Vibrio cholerae

Cholera is a severe diarrheal disease typically caused by O1 serogroup strains of Vibrio cholerae. The pathogenicity of all pandemic V. cholerae O1 strains relies on two critical virulence factors: cholera toxin, a potent enterotoxin, and toxin coregulated pilus (TCP), an intestinal colonization fac...

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Detalles Bibliográficos
Autores principales: Shin, Ok S., Tam, Vincent C., Suzuki, Masato, Ritchie, Jennifer M., Bronson, Roderick T., Waldor, Matthew K., Mekalanos, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111608/
https://www.ncbi.nlm.nih.gov/pubmed/21673189
http://dx.doi.org/10.1128/mBio.00106-11