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Zeranol Down-Regulates p53 Expression in Primary Cultured Human Breast Cancer Epithelial Cells through Epigenetic Modification

Epidemiological studies have suggested that there are many risk factors associated with breast cancer. Silencing tumor suppressor genes through epigenetic alterations play critical roles in breast cancer initiation, promotion and progression. As a growth promoter, Zeranol (Z) has been approved by th...

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Detalles Bibliográficos
Autores principales: Ye, Weiping, Xu, Pingping, Jen, Robert, Feng, Eric, Zhong, Saiyi, Li, Hong, Lin, Shu-Hong, Liu, Jie-Yu, Lin, Young C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111616/
https://www.ncbi.nlm.nih.gov/pubmed/21673905
http://dx.doi.org/10.3390/ijms12031519