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Docetaxel-Loaded Pluronic P123 Polymeric Micelles: in Vitro and in Vivo Evaluation

In this work, novel docetaxel (DTX) -loaded Tween 80-free Pluronic P123 (P123) micelles with improved therapeutic effect were developed. The freeze-dried DTX-loaded P123 micelles (DTX-micelles) were analyzed by HPLC, TEM and DLS to determine the DTX loading, micelle morphology, size, respectively. T...

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Detalles Bibliográficos
Autores principales: Liu, Zhihong, Liu, Donghua, Wang, Lili, Zhang, Juan, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111627/
https://www.ncbi.nlm.nih.gov/pubmed/21673916
http://dx.doi.org/10.3390/ijms12031684