IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

As an established mediator of inflammation, IL-6 is implicated to facilitate prostate cancer progression to androgen independence through transactivation of the androgen receptor. However, whether IL-6 plays a causative role in de novo prostate tumorigenesis was never investigated. We now provide th...

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Detalles Bibliográficos
Autores principales: Rojas, Andres, Liu, Gang, Coleman, Ilsa, Nelson, Peter S., Zhang, Miqin, Dash, Rupesh, Fisher, Paul B, Plymate, Stephen R., Wu, Jennifer D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112005/
https://www.ncbi.nlm.nih.gov/pubmed/21258401
http://dx.doi.org/10.1038/onc.2010.605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112005/
https://www.ncbi.nlm.nih.gov/pubmed/21258401
http://dx.doi.org/10.1038/onc.2010.605

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