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Do pharmacokinetic polymorphisms explain treatment failure in high-risk patients with neuroblastoma?

PURPOSE: Neuroblastoma is the most common extracranial solid tumour in childhood. It accounts for 15% of all paediatric oncology deaths. In the last few decades, improvement in treatment outcome for high-risk patients has not occurred, with an overall survival rate <30–40%. Many reasons may accou...

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Detalles Bibliográficos
Autores principales: Bellanti, Francesco, Kågedal, Bertil, Della Pasqua, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112027/
https://www.ncbi.nlm.nih.gov/pubmed/21287160
http://dx.doi.org/10.1007/s00228-010-0966-3