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A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression

BACKGROUND: Recent observations point towards the existence of a large number of neighborhoods composed of functionally-related gene modules that lie together in the genome. This local component in the distribution of the functionality across chromosomes is probably affecting the own chromosomal arc...

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Detalles Bibliográficos
Autores principales: Alloza, Eva, Al-Shahrour, Fátima, Cigudosa, Juan C, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112060/
https://www.ncbi.nlm.nih.gov/pubmed/21548942
http://dx.doi.org/10.1186/1755-8794-4-37