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A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression
BACKGROUND: Recent observations point towards the existence of a large number of neighborhoods composed of functionally-related gene modules that lie together in the genome. This local component in the distribution of the functionality across chromosomes is probably affecting the own chromosomal arc...
Autores principales: | Alloza, Eva, Al-Shahrour, Fátima, Cigudosa, Juan C, Dopazo, Joaquín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112060/ https://www.ncbi.nlm.nih.gov/pubmed/21548942 http://dx.doi.org/10.1186/1755-8794-4-37 |
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