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Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
BACKGROUND: Peroxisome proliferator-activated receptor-γ co-activator (PGC)-1α is a transcriptional co-activator of antioxidant genes and a master regulator of mitochondrial biogenesis. Parkinson's disease (PD) is associated with oxidative stress and mitochondrial dysfunction and recent work su...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112073/ https://www.ncbi.nlm.nih.gov/pubmed/21595954 http://dx.doi.org/10.1186/1471-2350-12-69 |