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Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease

BACKGROUND: Peroxisome proliferator-activated receptor-γ co-activator (PGC)-1α is a transcriptional co-activator of antioxidant genes and a master regulator of mitochondrial biogenesis. Parkinson's disease (PD) is associated with oxidative stress and mitochondrial dysfunction and recent work su...

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Detalles Bibliográficos
Autores principales:	Clark, Joanne, Reddy, Sonika, Zheng, Kangni, Betensky, Rebecca A, Simon, David K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112073/ https://www.ncbi.nlm.nih.gov/pubmed/21595954 http://dx.doi.org/10.1186/1471-2350-12-69

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