Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study

T cell directed HIV vaccines are based upon the induction of CD8+ T cell memory responses that would be effective in inhibiting infection and subsequent replication of an infecting HIV-1 strain, a process that requires a match or near-match between the epitope induced by vaccination and the infectin...

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Detalles Bibliográficos
Autores principales: Li, Fusheng, Finnefrock, Adam C., Dubey, Sheri A., Korber, Bette T. M., Szinger, James, Cole, Suzanne, McElrath, M. Juliana, Shiver, John W., Casimiro, Danilo R., Corey, Lawrence, Self, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112144/
https://www.ncbi.nlm.nih.gov/pubmed/21695251
http://dx.doi.org/10.1371/journal.pone.0020479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112144/
https://www.ncbi.nlm.nih.gov/pubmed/21695251
http://dx.doi.org/10.1371/journal.pone.0020479

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