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Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study
T cell directed HIV vaccines are based upon the induction of CD8+ T cell memory responses that would be effective in inhibiting infection and subsequent replication of an infecting HIV-1 strain, a process that requires a match or near-match between the epitope induced by vaccination and the infectin...
Autores principales: | Li, Fusheng, Finnefrock, Adam C., Dubey, Sheri A., Korber, Bette T. M., Szinger, James, Cole, Suzanne, McElrath, M. Juliana, Shiver, John W., Casimiro, Danilo R., Corey, Lawrence, Self, Steven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112144/ https://www.ncbi.nlm.nih.gov/pubmed/21695251 http://dx.doi.org/10.1371/journal.pone.0020479 |
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