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HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop
BACKGROUND: Stat3 is a cytokine- and growth factor-inducible transcription factor that regulates cell motility, migration, and invasion under normal and pathological situations, making it a promising target for cancer therapeutics. The hepatocyte growth factor (HGF)/c-met receptor tyrosine kinase si...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112164/ https://www.ncbi.nlm.nih.gov/pubmed/21595927 http://dx.doi.org/10.1186/1471-2407-11-180 |