The Oncoprotein EVI1 and the DNA Methyltransferase Dnmt3 Co-Operate in Binding and De Novo Methylation of Target DNA

EVI1 has pleiotropic functions during murine embryogenesis and its targeted disruption leads to prenatal death by severely affecting the development of virtually all embryonic organs. However, its functions in adult tissues are still unclear. When inappropriately expressed, EVI1 becomes one of the m...

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Detalles Bibliográficos
Autores principales: Senyuk, Vitalyi, Premanand, Kavitha, Xu, Peng, Qian, Zhijian, Nucifora, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112226/
https://www.ncbi.nlm.nih.gov/pubmed/21695170
http://dx.doi.org/10.1371/journal.pone.0020793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112226/
https://www.ncbi.nlm.nih.gov/pubmed/21695170
http://dx.doi.org/10.1371/journal.pone.0020793

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