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Relationship of porcine IGF2 imprinting status to DNA methylation at the H19 DMD and the IGF2 DMRs 1 and 2

BACKGROUND: Porcine IGF2 and the H19 genes are imprinted. The IGF2 is paternally expressed, while the H19 gene is maternally expressed. Extensive studies in mice established a boundary model indicating that the H19 differentially methylated domain (DMD) controls, upon binding with the CTCF protein,...

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Detalles Bibliográficos
Autores principales: Braunschweig, Martin H, Owczarek-Lipska, Marta, Stahlberger-Saitbekova, Nasikhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112248/
https://www.ncbi.nlm.nih.gov/pubmed/21575277
http://dx.doi.org/10.1186/1471-2156-12-47