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miRNAs as serum biomarkers for Duchenne muscular dystrophy

Dystrophin absence in Duchenne muscular dystrophy (DMD) causes severe muscle degeneration. We describe that, as consequence of fibre damage, specific muscle-miRNAs are released in to the bloodstream of DMD patients and their levels correlate with the severity of the disease. The same miRNAs are abun...

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Detalles Bibliográficos
Autores principales: Cacchiarelli, Davide, Legnini, Ivano, Martone, Julie, Cazzella, Valentina, D'Amico, Adele, Bertini, Enrico, Bozzoni, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112257/
https://www.ncbi.nlm.nih.gov/pubmed/21425469
http://dx.doi.org/10.1002/emmm.201100133