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Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants

Placental hCG and pitutary LH transduce signals in target tissues through a common receptor (LHCGR). We demonstrate that recombinant LHCGR proteins which include the hormone-binding domain are secreted from transfected cells and that natural LHCGR is also secreted from human placental explants. LHCG...

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Detalles Bibliográficos
Autores principales: Chambers, Anne E, Stanley, Paul F, Randeva, Harpal, Banerjee, Subhasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112408/
https://www.ncbi.nlm.nih.gov/pubmed/21575145
http://dx.doi.org/10.1186/1477-7827-9-64