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Lipid phosphate phosphatase-3 regulates tumor growth via β-catenin and Cyclin-D1 signaling

BACKGROUND: The acquisition of proliferative and invasive phenotypes is considered a hallmark of neoplastic transformation; however, the underlying mechanisms are less well known. Lipid phosphate phosphatase-3 (LPP3) not only catalyzes the dephosphorylation of the bioactive lipid sphingosine-1-phosp...

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Detalles Bibliográficos
Autores principales: Chatterjee, Ishita, Humtsoe, Joseph O, Kohler, Erin E, Sorio, Claudio, Wary, Kishore K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112429/
https://www.ncbi.nlm.nih.gov/pubmed/21569306
http://dx.doi.org/10.1186/1476-4598-10-51