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A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine

BACKGROUND: Amodiaquine (AQ) along with sulphadoxine-pyrimethamine (SP) offers effective and cheaper treatment against chloroquine-resistant falciparum malaria in many parts of sub-Saharan Africa. Considering the previous history of hepatitis, agranulocytosis and neutrocytopenia associated with AQ m...

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Detalles Bibliográficos
Autores principales: Mishra, Shrawan Kumar, Singh, Prabhat, Rath, Srikanta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112449/
https://www.ncbi.nlm.nih.gov/pubmed/21529379
http://dx.doi.org/10.1186/1475-2875-10-109