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Meta-analysis of randomized trials comparing thiopurines in childhood acute lymphoblastic leukaemia
Mercaptopurine has been used in continuing treatment for childhood acute lymphoblastic leukaemia since the mid 1950s. Recent advances in the understanding of thiopurine pharmacology indicated thioguanine might be more effective than mercaptopurine. The US and UK cooperative groups began randomized t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112460/ https://www.ncbi.nlm.nih.gov/pubmed/21372841 http://dx.doi.org/10.1038/leu.2011.37 |