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Meta-analysis of randomized trials comparing thiopurines in childhood acute lymphoblastic leukaemia

Mercaptopurine has been used in continuing treatment for childhood acute lymphoblastic leukaemia since the mid 1950s. Recent advances in the understanding of thiopurine pharmacology indicated thioguanine might be more effective than mercaptopurine. The US and UK cooperative groups began randomized t...

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Detalles Bibliográficos
Autores principales: Escherich, Gabriele M, Richards, Sue, Stork, Linda C, Vora, Ajay J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112460/
https://www.ncbi.nlm.nih.gov/pubmed/21372841
http://dx.doi.org/10.1038/leu.2011.37