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Delayed repair of radiation induced clustered DNA damage: Friend or foe?

A signature of ionizing radiation exposure is the induction of DNA clustered damaged sites, defined as two or more lesions within one to two helical turns of DNA by passage of a single radiation track. Clustered damage is made up of double strand breaks (DSB) with associated base lesions or abasic (...

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Detalles Bibliográficos
Autores principales: Eccles, Laura J., O’Neill, Peter, Lomax, Martine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112496/
https://www.ncbi.nlm.nih.gov/pubmed/21130102
http://dx.doi.org/10.1016/j.mrfmmm.2010.11.003