Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubules. Aurora B kinase indirectly invokes this checkpoint by destabilizing incorrect attachments; however, a more direct role remains controversial. In contrast, activity of the kinase Mps1 is indispens...

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Detalles Bibliográficos
Autores principales: Saurin, Adrian T., van der Waal, Maike S., Medema, René H., Lens, Susanne M.A., Kops, Geert J.P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113227/
https://www.ncbi.nlm.nih.gov/pubmed/21587233
http://dx.doi.org/10.1038/ncomms1319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113227/
https://www.ncbi.nlm.nih.gov/pubmed/21587233
http://dx.doi.org/10.1038/ncomms1319

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