Cargando…
Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis
The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubules. Aurora B kinase indirectly invokes this checkpoint by destabilizing incorrect attachments; however, a more direct role remains controversial. In contrast, activity of the kinase Mps1 is indispens...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113227/ https://www.ncbi.nlm.nih.gov/pubmed/21587233 http://dx.doi.org/10.1038/ncomms1319 |