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Predicting sites of ADAR editing in double-stranded RNA

ADAR (adenosine deaminase that acts on RNA) editing enzymes target coding and noncoding double-stranded RNA (dsRNA) and are essential for neuronal function. Early studies showed that ADARs preferentially target adenosines with certain 5′ and 3′ neighbours. Here we use current Sanger sequencing proto...

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Detalles Bibliográficos
Autores principales: Eggington, Julie M., Greene, Tom, Bass, Brenda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113232/
https://www.ncbi.nlm.nih.gov/pubmed/21587236
http://dx.doi.org/10.1038/ncomms1324