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Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

BACKGROUND: Previous studies indicate a role of P2X(7 )receptors in processes that lead to neuronal death. The main objective of our study was to examine whether genetic deletion or pharmacological blockade of P2X(7 )receptors influenced dopaminergic cell death in various models of Parkinson's...

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Detalles Bibliográficos
Autores principales: Hracskó, Zsuzsanna, Baranyi, Mária, Csölle, Cecilia, Gölöncsér, Flóra, Madarász, Emilia, Kittel, Ágnes, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113297/
https://www.ncbi.nlm.nih.gov/pubmed/21542899
http://dx.doi.org/10.1186/1750-1326-6-28