Cargando…
Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease
BACKGROUND: Previous studies indicate a role of P2X(7 )receptors in processes that lead to neuronal death. The main objective of our study was to examine whether genetic deletion or pharmacological blockade of P2X(7 )receptors influenced dopaminergic cell death in various models of Parkinson's...
Autores principales: | Hracskó, Zsuzsanna, Baranyi, Mária, Csölle, Cecilia, Gölöncsér, Flóra, Madarász, Emilia, Kittel, Ágnes, Sperlágh, Beáta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113297/ https://www.ncbi.nlm.nih.gov/pubmed/21542899 http://dx.doi.org/10.1186/1750-1326-6-28 |
Ejemplares similares
-
The double-faced role of P2X(7) receptors in toxin-induced animal models of Parkinson’s disease
por: Sperlágh, Beáta, et al.
Publicado: (2011) -
The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice
por: Csölle, Cecilia, et al.
Publicado: (2013) -
Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors
por: Csölle, Cecilia, et al.
Publicado: (2013) -
Learned helplessness paradigm in P2xr7 wild type and knock out mice and its effect on synapses in the dentate gyrus
por: Otrokocsi, Lilla, et al.
Publicado: (2015) -
Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine
por: Gölöncsér, Flóra, et al.
Publicado: (2014)