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Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis

Accumulation of misfolded neurotoxic Cu, Zn-superoxide dismutase-1 (SOD1) protein found in both familial and sporadic amyotrophic lateral sclerosis (ALS) is recognized as an important contributing factor of neuronal cell death. However, little is known about the mechanisms controlling the accumulati...

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Detalles Bibliográficos
Autores principales: Ren, Guijie, Ma, Zhongcai, Hui, Maria, Kudo, Lili C, Hui, Koon-Sea, Karsten, Stanislav L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113298/
https://www.ncbi.nlm.nih.gov/pubmed/21548977
http://dx.doi.org/10.1186/1750-1326-6-29