Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain

1. ABSTRACT: BACKGROUND: Cyclic phosphatidic acid (cPA) is a structural analog of lysophosphatidic acid (LPA), but possesses different biological functions, such as the inhibition of autotaxin (ATX), an LPA-synthesizing enzyme. As LPA is a signaling molecule involved in nociception in the peripheral...

Descripción completa

Detalles Bibliográficos
Autores principales: Kakiuchi, Yasutaka, Nagai, Jun, Gotoh, Mari, Hotta, Harumi, Murofushi, Hiromu, Ogawa, Tomoyo, Ueda, Hiroshi, Murakami-Murofushi, Kimiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113318/
https://www.ncbi.nlm.nih.gov/pubmed/21569544
http://dx.doi.org/10.1186/1744-8069-7-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113318/
https://www.ncbi.nlm.nih.gov/pubmed/21569544
http://dx.doi.org/10.1186/1744-8069-7-33

Ejemplares similares