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Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain
1. ABSTRACT: BACKGROUND: Cyclic phosphatidic acid (cPA) is a structural analog of lysophosphatidic acid (LPA), but possesses different biological functions, such as the inhibition of autotaxin (ATX), an LPA-synthesizing enzyme. As LPA is a signaling molecule involved in nociception in the peripheral...
Autores principales: | Kakiuchi, Yasutaka, Nagai, Jun, Gotoh, Mari, Hotta, Harumi, Murofushi, Hiromu, Ogawa, Tomoyo, Ueda, Hiroshi, Murakami-Murofushi, Kimiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113318/ https://www.ncbi.nlm.nih.gov/pubmed/21569544 http://dx.doi.org/10.1186/1744-8069-7-33 |
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