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Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats
BACKGROUND: Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals. Ion channels play a vital role in pain signal initiation and conduction. Activation of K(ATP )channels has been implicated in mediating the analgesic effects of agents such as morphine. However, sy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113320/ https://www.ncbi.nlm.nih.gov/pubmed/21569593 http://dx.doi.org/10.1186/1744-8069-7-35 |