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Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats

BACKGROUND: Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals. Ion channels play a vital role in pain signal initiation and conduction. Activation of K(ATP )channels has been implicated in mediating the analgesic effects of agents such as morphine. However, sy...

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Detalles Bibliográficos
Autores principales: Du, Xiaona, Wang, Chao, Zhang, Hailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113320/
https://www.ncbi.nlm.nih.gov/pubmed/21569593
http://dx.doi.org/10.1186/1744-8069-7-35