Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity

BACKGROUND: 3,4-Methylenedioxymethamphetamine (MDMA) produces a neuroinflammatory reaction in rat brain characterized by an increase in interleukin-1 beta (IL-1β) and microglial activation. The CB2 receptor agonist JWH-015 reduces both these changes and partially protects against MDMA-induced neurot...

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Detalles Bibliográficos
Autores principales: Torres, Elisa, Gutierrez-Lopez, Maria D, Mayado, Andrea, Rubio, Ana, O'Shea, Esther, Colado, Maria I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113340/
https://www.ncbi.nlm.nih.gov/pubmed/21595923
http://dx.doi.org/10.1186/1742-2094-8-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113340/
https://www.ncbi.nlm.nih.gov/pubmed/21595923
http://dx.doi.org/10.1186/1742-2094-8-53

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