Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior

BACKGROUND: Interleukin (IL)-6 is produced in the brain during peripheral infection and plays an important but poorly understood role in sickness behavior. Therefore, this study investigated the capacity of soluble gp130 (sgp130), a natural inhibitor of the IL-6 trans-signaling pathway to regulate I...

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Detalles Bibliográficos
Autores principales: Burton, Michael D, Sparkman, Nathan L, Johnson, Rodney W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113341/
https://www.ncbi.nlm.nih.gov/pubmed/21595956
http://dx.doi.org/10.1186/1742-2094-8-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113341/
https://www.ncbi.nlm.nih.gov/pubmed/21595956
http://dx.doi.org/10.1186/1742-2094-8-54

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