Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C(2)H(2) zinc fingers

Sequence-specific DNA recognition by gene regulatory proteins is critical for proper cellular functioning. The ability to predict the DNA binding preferences of these regulatory proteins from their amino acid sequence would greatly aid in reconstruction of their regulatory interactions. Structural m...

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Detalles Bibliográficos
Autores principales: Yanover, Chen, Bradley, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113574/
https://www.ncbi.nlm.nih.gov/pubmed/21343182
http://dx.doi.org/10.1093/nar/gkr048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113574/
https://www.ncbi.nlm.nih.gov/pubmed/21343182
http://dx.doi.org/10.1093/nar/gkr048

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