Using a structural and logics systems approach to infer bHLH–DNA binding specificity determinants

Numerous efforts are underway to determine gene regulatory networks that describe physical relationships between transcription factors (TFs) and their target DNA sequences. Members of paralogous TF families typically recognize similar DNA sequences. Knowledge of the molecular determinants of protein...

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Detalles Bibliográficos
Autores principales: De Masi, Federico, Grove, Christian A., Vedenko, Anastasia, Alibés, Andreu, Gisselbrecht, Stephen S., Serrano, Luis, Bulyk, Martha L., Walhout, Albertha J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113581/
https://www.ncbi.nlm.nih.gov/pubmed/21335608
http://dx.doi.org/10.1093/nar/gkr070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113581/
https://www.ncbi.nlm.nih.gov/pubmed/21335608
http://dx.doi.org/10.1093/nar/gkr070

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