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Using a structural and logics systems approach to infer bHLH–DNA binding specificity determinants
Numerous efforts are underway to determine gene regulatory networks that describe physical relationships between transcription factors (TFs) and their target DNA sequences. Members of paralogous TF families typically recognize similar DNA sequences. Knowledge of the molecular determinants of protein...
Autores principales: | De Masi, Federico, Grove, Christian A., Vedenko, Anastasia, Alibés, Andreu, Gisselbrecht, Stephen S., Serrano, Luis, Bulyk, Martha L., Walhout, Albertha J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113581/ https://www.ncbi.nlm.nih.gov/pubmed/21335608 http://dx.doi.org/10.1093/nar/gkr070 |
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