Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing

Little is known about whether components of the RNA-induced silencing complex (RISC) mediate the biogenesis of RNAs other than miRNA. Here, we show that depletion of key proteins of the RISC pathway by antisense oligonucleotides significantly impairs pre-rRNA processing in human cells. In cells depl...

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Detalles Bibliográficos
Autores principales: Liang, Xue-hai, Crooke, Stanley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113584/
https://www.ncbi.nlm.nih.gov/pubmed/21321021
http://dx.doi.org/10.1093/nar/gkr076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113584/
https://www.ncbi.nlm.nih.gov/pubmed/21321021
http://dx.doi.org/10.1093/nar/gkr076

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