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Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing
Little is known about whether components of the RNA-induced silencing complex (RISC) mediate the biogenesis of RNAs other than miRNA. Here, we show that depletion of key proteins of the RISC pathway by antisense oligonucleotides significantly impairs pre-rRNA processing in human cells. In cells depl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113584/ https://www.ncbi.nlm.nih.gov/pubmed/21321021 http://dx.doi.org/10.1093/nar/gkr076 |